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DESIGN OF DISEASE SPECIFIC AGENTS FOR DIAGNOSTICS AND THERAPEUTICS BASED ON THE PROTEIN ISOFORM OF VEGF, HER-2, PSA
DESIGN OF DISEASE SPECIFIC AGENTS FOR DIAGNOSTICS AND THERAPEUTICS BASED ON THE PROTEIN ISOFORM OF VEGF, HER-2, PSA
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机译:基于VEGF,HER-2,PSA蛋白同工型的诊断和治疗疾病特异性药物的设计
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摘要
Provided herein are methods for making and screening antibodies. Methods may include injecting a plurality of antigens or nucleic acids encoding antigens into a host. Methods may also include using fusion proteins of an antigen to a carrier protein for preparing and/or screening antibody preparations. The methods may be used for simultaneous making and/or screening of large numbers of different antibodies. Also provided herein are therapeutic and diagnostic methods for treating, preventing or diagnosing a disease or the likelihood of developing a disease that is associated with an isoform of a protein.
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