首页> 外国专利> METHOD FOR MEASURING FCRII/CD23 IGE RECEPTOR IN HUMAN FECES AS AN INDICATOR OF A TH2 PREDOMINANT IMMUNE RESPONSE INVOLVED IN GASTROINTESTINAL ILLNESSES

METHOD FOR MEASURING FCRII/CD23 IGE RECEPTOR IN HUMAN FECES AS AN INDICATOR OF A TH2 PREDOMINANT IMMUNE RESPONSE INVOLVED IN GASTROINTESTINAL ILLNESSES

机译:作为人胃肠道疾病中TH2优势免疫反应指标的人类粪便中FCRII / CD23 IGE受体的测定方法

摘要

A method and apparatus for measuring FcRII/CD23 IgE receptor in human feces or other biological specimens as an indicator of a TH2 immune response indicative of gastrointestinal illnesses such as ulcerative colitis and food allergy is described. The apparatus consists of either a qualitative or quantitative enzyme-linked immunoassay or other immunoassay that utilizes antibodies specific to human FcRII/CD23 IgE receptor for the measurement of endogenous FcRII/CD23 IgE receptor in human feces. The method and apparatus can be used by healthcare providers as an aid for determining gastrointestinal illnesses that are predominantly a TH2 predominant immune response such as ulcerative colitis, large bowel Crohn's disease (UC-like Crohn's disease), allergic colitis (food allergy) and parasitic infections.
机译:描述了一种用于测量人粪便或其他生物样本中的FcRII / CD23 IgE受体的方法和装置,作为指示胃肠道疾病(如溃疡性结肠炎和食物过敏)的TH2免疫反应的指标。该仪器由定性或定量酶联免疫测定或其他免疫测定组成,该测定利用对人FcRII / CD23 IgE受体具有特异性的抗体来测量人粪便中的内源性FcRII / CD23 IgE受体。该方法和装置可以被医疗保健提供者用作确定主要以TH2为主的免疫反应的胃肠道疾病的辅助手段,例如溃疡性结肠炎,大肠克罗恩氏病(类似UC的克罗恩氏病),过敏性结肠炎(食物过敏)和寄生虫病感染。

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