GENE THERAPY FOR SKIN DISEASES USING NEEDLE FREE SYRINGE

摘要

It is intended to provide a clinically useful therapeutic method for skin diseases, in particular, intractable skin diseases. More specifically speaking, a polynucleotide such as DNA, oligonucleotide, RNA, siRNA or antisense is injected around a skin disease (wound, skin ulcer, psoriasis, etc.) site or subcutaneously introduced in a single dose of 10 μg to 10 mg by using a needle free syringe whereby a liquid drug is injected by moving a piston with the use of a gas pressure or the elastic force of an elastic member.