CANINE INTERLEUKIN 18, CANINE INTERLEUKIN 1$g(b) CONVERTASE, DNA SEQUENCES ENCODING THE SAME, PROCESS FOR PRODUCING INTERLE UKIN 18, AND REMEDIES FOR CANINE IMMUNOLOGICAL DISEASES

摘要

Canine interleukin 18, a process for producing the same in insect cells or larvae, etc. The canine interleukin 18 has at least one capability selected from among the capability of acting on canine leukocytes to thereby induce an antiviral activity factor and a factor potentiating the expression of class II MHC on canine tumor cells, the one of promoting the proliferation of canine lymphocytes, the one of injuring and killing canine lymphocytes and canine tumor cells, the one of lessening tumors in vital canine bodies, and the one of activating canine leukocytes to thereby suppress canine allergy.