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COMPETITIVE INHIBITORS OF GLYOXALASE I AND METHOD OF GENERATING SUCH COMPETITIVE INHIBITORS INSIDE TUMOR CELLS
COMPETITIVE INHIBITORS OF GLYOXALASE I AND METHOD OF GENERATING SUCH COMPETITIVE INHIBITORS INSIDE TUMOR CELLS
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机译:乙二醛酶I的竞争性抑制剂和在肿瘤细胞内产生这种竞争性抑制剂的方法
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摘要
The present invention provides a compound having the structure wherein S* is S=O or O=S=O; and wherein R1 is selected from the group consisting of (C1-C9) alkyl, (C3-C8) cycloalkyl, (C5-C7) cycloalkenyl, and (C6-C20) aryl substituted with halogen or (C1-C18) alkyl; and wherein R2 is selected from the group consisting of alkyl, (C1-C9) alkyl, (C3-C8) cycloalkyl, (C5-C7) cycloalkenyl, and (C6-C20) aryl substituted with halogen or (C1-C18) alkyl. Also provided are various methods of using the compositions of the present invention.
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机译:本发明提供具有以下结构的化合物,其中S *为S = O或O = S = O;其中R1选自由(C1-C9)烷基,(C3-C8)环烷基,(C5-C7)环烯基和被卤素或(C1-C18)烷基取代的芳基的(C6-C20)芳基组成的组;其中R2选自烷基,(C1-C9)烷基,(C3-C8)环烷基,(C5-C7)环烯基和被卤素或(C1-C18)烷基取代的(C6-C20)芳基。还提供了使用本发明的组合物的各种方法。
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