A SUPERANTIGEN FUSION PROTEIN USED FOR ANTITUMOR THERAPY AND THE PREPARATION THEREOF

摘要

This invention provides a fusion protein containing: a) a ligand which promotes the growth of the cancer cell and corresponds to the receptor of cancer cell overexpression, an artificial screened polypeptid which has avidity and antagonism to the receptor of cancer cell or the polypeptid molecule which may affect directly to the cancer cell surface; b) a superantigen which may lead to the antitumor immunological reaction. A expression vector and a host cell containing this fusion proteîn the preparation method thereof and the usage of this fusion protein to made the medicines for antitumor therapy or immunological reaction were also disclosed by the present invention.