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PAEL RECEPTOR, CELLS AND ANIMAL EXPRESSING PAEL RECEPTOR AND METHOD OF SCREENING REMEDY FOR PARKINSON'S DISEASE
PAEL RECEPTOR, CELLS AND ANIMAL EXPRESSING PAEL RECEPTOR AND METHOD OF SCREENING REMEDY FOR PARKINSON'S DISEASE
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机译:帕金森氏病,细胞和动物表达的帕金森氏病以及筛查帕金森氏病的方法
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摘要
A human Pael receptor for screening remedies for Parkinson's disease, is new. Independent claims are also included for: (1) animals cells for similar drug screening having a DNA that encodes a foreign human Pael receptor or a DNA that carries its variant integrated; (2) non-human mammals having a DNA carrying the DNA integrated; (3) cells isolated from the mammals; (4) screening remedies for Parkinson's disease by contacting a candidate compound with the human Pael receptor or the animal cells, or by administering it into the non-human mammals, with the amount of Pael receptor in the cells in such animals as indication; (5) probes containing the whole or a part of the DNA encoding the human Pael receptor for detecting risk factor for onset of Parkinson's disease; (6) detecting risk factor for onset of Parkinson's disease by using the probes; and (7) an antibody recognizing the Pael receptor by reacting with such receptor but not with the Pael receptor homolog of ETBR-LP-2. ACTIVITY : Antiparkinsonism. No suitable data given. MECHANISM OF ACTION : None given.
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