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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN MELATONIN RECEPTOR TYPE 1A (MTNR1A)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN MELATONIN RECEPTOR TYPE 1A (MTNR1A)
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机译:1A型人类褪黑素受体(MTNR1A)相关疾病的诊断和治疗
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摘要
The invention provides a human MTNR1A which is associated with the cardiovascular diseases, endocrinological diseases, metabolic diseases, inflammation, gastroenterological diseases, cancer, hematological diseases, respiratory diseaes, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, endocrinological diseases, metabolic diseases, inflammation, gastroenterological diseases, cancer, hematological diseases, respiratory diseaes, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of MTNR1A as well as pharmaceutical compositions comprising such compounds.
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