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METHOD FOR DETERMINING SPECIFIC GROUPS CONSTITUTING HEPARINS OR LOW MOLECULAR WEIGHT HEPARINS USING REVERSED PHASE COLUMN CHROMATOGRAPHY
METHOD FOR DETERMINING SPECIFIC GROUPS CONSTITUTING HEPARINS OR LOW MOLECULAR WEIGHT HEPARINS USING REVERSED PHASE COLUMN CHROMATOGRAPHY
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机译:反相色谱法测定组成肝素或低分子量肝素的特定基团的方法
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摘要
The invention provides methods for analysing heparins, low-molecular-weight heparins, ultralow-molecular-weight heparins, and oligosaccharides by high performance liquid chromatography a stationary phase dynamically coated with a quaternary ammonium salt. The methods of the invention may be used to analyse samples without pre-treatment or to analyse samples that have been partially or exhaustively depolymerised and, optionally, reduced. Specific saccharides can be detected.
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