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POLYMORPHISM OF SOAT1 USEFUL FOR IDENTIFYING RISK OF DEVELOPING ALZHEIMER'S DISEASE
POLYMORPHISM OF SOAT1 USEFUL FOR IDENTIFYING RISK OF DEVELOPING ALZHEIMER'S DISEASE
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机译:SOAT1的多态性可用于识别发展中的老年痴呆症的风险
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摘要
Based on the unexpected association of a SOAT1 gene polymorphism with reduced genetic risk for a neurodegenerative disease, in particular Alzheimer's disease, the present invention provides a method of diagnosing or prognosticating such a disease, or determining the propensity or predisposition of a subject to develop such a disease. The method comprises detecting the presence or absence of a single nucleotide polymorphism in the SOAT1 gene which encodes the enzmye ACAT1, acyl-coenzyme A: cholesterol acyltransferase 1.
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