首页> 外国专利> INCREASE OF THE IMMUNE RESPONSE BY SUBSTANCES INFLUENCING THE FUNCTION OF NATURAL KILLER CELLS

INCREASE OF THE IMMUNE RESPONSE BY SUBSTANCES INFLUENCING THE FUNCTION OF NATURAL KILLER CELLS

机译:影响天然杀伤细胞功能的物质增加的免疫反应

摘要

The invention relates to an active ingredient comprising a first molecular constituent which binds to a first molecule selected from the group consisting of "NCAM, KIR2DL, KIR2DS, KIR3DL, CD94/CD159, CD57, CD85, CD16, NKp30, NKp44, NKp46, NKG2D and CD244", and a second molecular constituent which binds to a second molecule selected from the group consisting of "CD2, CD4, CD44, CD69 and T-cell-receptor", the first and the second molecular constituents being covalently bonded. The invention also relates to the use of said active ingredient for producing a pharmaceutical composition for stimulating the immune system.
机译:本发明涉及包含与第一分子结合的第一分子成分的活性成分,所述第一分子选自:“ NCAM,KIR2DL,KIR2DS,KIR3DL,CD94 / CD159,CD57,CD85,CD16,NKp30,NKp44,NKp46,NKG2D和CD244”,以及与第二分子结合的第二分子成分,该第二分子选自“ CD2,CD4,CD44,CD69和T细胞受体”,第一和第二分子成分共价键合。本发明还涉及所述活性成分在生产用于刺激免疫系统的药物组合物中的用途。

著录项

  • 公开/公告号EP1590370A1

    专利类型

  • 公开/公告日2005-11-02

    原文格式PDF

  • 申请/专利权人 UNIVERSITAET ZU KOELN;

    申请/专利号EP20030813541

  • 申请日2003-12-19

  • 分类号C07K16/28;A61K39/395;C07K14/74;C07K14/705;C07K14/11;C07K14/115;A61K38/17;A61P37/00;

  • 国家 EP

  • 入库时间 2022-08-21 22:06:39

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