METHOD FOR INCREASING CONTENT OF GAMMA-AMINOBUTYRIC ACID OF GINGKO LEAVES, THEREBY IMPROVING CRANIAL BLOOD FLOW, BRAIN METABOLISM, BLOOD CIRCULATION AND BRAIN DYSFUNCTION

摘要

PURPOSE: A method of increasing the content of gamma-aminobutyric acid in gingko leaves by substituting air in an air tight container containing gingko leaves with carbon dioxide or nitrogen gas, inoculating lactic acid bacteria into the medium containing glutamic acid or glutamate and then fermenting the medium is provided. The product has an action of improving cranial blood flow, brain metabolism, blood circulation and brain dysfunction and can be used as a functional food, drugs or a material for the above medicinal action. CONSTITUTION: Gingko leaves are introduced into an air tight container, air in the container is substituted with carbon dioxide or nitrogen gas and then left alone at 20 to 30deg.C for 30min to 24hr to increase the content of gamma-aminobutyric acid in gingko leaves in the first stage. Thereafter, gingko leaves having increased content of gamma-aminobutyric acid are ground, mixed with 1 to 5% by weight of glutamic acid or glutamate and added to a medium, which is inoculated with 0.5 to 1% by weight of lactic acid bacteria and fermented for 36hr to increase the content of gamma-aminobutyric acid in gingko leaves in the second stage.