METHOD FOR VISUALIZING LARGE-SCALE PROTEIN-PROTEIN INTERACTION NETWORK

摘要

PURPOSE: A method for visualizing large-scale protein-protein interaction network is provided to visualize the protein-protein interaction network fast and simply by adjusting a position of each node to a center of neighboring nodes of each node after preferentially arranging all connected components in the network and arranging the nodes to the center of a pivot node in the connected component. CONSTITUTION: The connected component in the protein-protein interaction network is identified/arranged. A middle node and the pivot node in each connected component are determined. A distance to each node from the pivot node within each connected component is respectively calculated and each node related to the pivot node is arranged based on the calculated distance. Each connected component is rearranged by arranging a cut-vertex related to the middle node and the middle node related to the neighboring node of the cut-vertex. Each connected component is rearranged by arranging each node to the neighboring node within the distance fixed to each node as the center.