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BIODEGRADABLE BIO-ABSORBABLE MATERIAL FOR CLINICAL PRACTICE AND METHOD FOR PRODUCING THE SAME

机译:临床上可生物降解的生物可吸收材料及其生产方法

摘要

Bioabsorbable polymers employed as medical materials such as vascular stents and sutures have almost constant dynamic properties (tensile strength, etc.) and degradation speed due to absorption. In case of improving these dynamic properties, then these materials become fragile and the degradation speed is lowered. In case of elevating the degradation speed, then the dynamic properties are worsened and, as a result, there arises a problem that the purpose and site of using are restricted. Under these circumstances, a bioabsorbable polymer is copolymerized with a cyclic depsipeptide to give a copolymer having the ring-opening copolymerized depsipeptide. Thus, the dynamic properties and degradation speed can be controlled depending on the content of the depsipeptide.
机译:用作医疗材料(如血管支架和缝合线)的可生物吸收的聚合物具有几乎恒定的动态特性(抗张强度等)和由于吸收而引起的降解速度。在改善这些动态性能的情况下,这些材料变得易碎并且降解速度降低。在提高降解速度的情况下,动态性能变差,结果,出现了限制使用目的和场所的问题。在这些情况下,将可生物吸收的聚合物与环状二肽结合,得到具有开环共聚二肽的共聚物。因此,可以根据二肽的含量来控制动力学性质和降解速度。

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