A process for the preparation of a liquid formulation comprising amprolium and sulfaquinoxaline

摘要

PURPOSE: Provided is a process for the preparation of a liquid formulation comprising amprolium and sulfaquinoxaline, thereby producing a stable formulation comprising amprolium and sulfaquinoxaline without precipitates or floats. The prepared formulation keeps its won efficacy and stability even orally administered into livestock. CONSTITUTION: The process for the preparation of a liquid formulation comprising amprolium and sulfaquinoxaline comprises the steps of: (a) adding sodium hydroxide or potassium hydroxide to sodium sulfaquinoxaline; (b) adding N-methylpyrrolidone or dimethylsulfoxide to the solution obtained in the step(a), followed by dissolution; and (c) adding amprolium hydrochloride to the solution obtained in the step(b), followed by dissolution.