CASCADED HYDRODYNAMIC FOCUSING IN MICROFLUIDIC CHANNELS

摘要

Device according to the present invention is a body structure (body structure) having a plurality of fine fluid conduit formed therein and provided with the central conduit in fluid communication with the concentrate conduit which via a central pipe, and a plurality of cascade expression confluence (cascaded junction) It includes. Also the method of the present invention includes the steps of providing a body structure having a plurality of fine fluid conduit formed therein and provided with the central conduit in fluid communication with the concentrate conduit which via a central pipe, and a plurality of cascade type junction. The method also includes the ratio of the sheath fluid flowing in the central conduit through the steps of: providing a step, flow of sheath fluid in said concentrate conduit to provide a flow of sample fluid in the central conduit, and the concentrate conduit and a cascade expression confluence by adjusting comprises the step of controlling the concentration or flow of the sample fluid. The apparatus and method of the present invention may be useful in controlling or concentrate the flow of sample fluid in the microfluidic processes. In addition, the apparatus and method can be useful for detecting molecules that target within the microfluidic processes.