Kit for the Diagnosis of Chronic Respiratory and Pancreatic Diseases Associated with CFTR variants in East Asian

摘要

PURPOSE: A kit for diagnosis of chronic respiratory and pancreatic diseases associated with CFTR variants in east Asian is provided, which CFTR(cystic fibrosis transmembrane conductance regulator) variants that are frequently occurred in east Asian are identified, so that the accuracy of the diagnosis can be improved. CONSTITUTION: The kit for diagnosis of chronic respiratory and pancreatic diseases associated with CFTR variants in east Asian comprises: at least one nucleic acid molecule selected from a nucleic acid molecule having the nucleotide sequence of SEQ ID NO:7 which comprises 782th nucleotide G in the CFTR gene having the nucleotide sequence of SEQ ID NO:1, and consists of 20 to 100 consecutive DNAs comprising the 782th nucleotide G; a nucleic acid molecule having the nucleotide sequence of SEQ ID NO:8 which comprises 1540th nucleotide G in the CFTR gene having the nucleotide sequence of SEQ ID NO:1, and consists of 20 to 100 consecutive DNAs comprising the 1540th nucleotide G; and a nucleic acid molecule having the nucleotide sequence of SEQ ID NO:9 which comprises 4188th nucleotide C in the CFTR gene having the nucleotide sequence of SEQ ID NO:1, and consists of 20 to 100 consecutive DNAs comprising the 4188th nucleotide C.