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CARBAMATE COMPOUNDS FOR USE FOR PREVENTION OR TREATMENT OF NEUROPATHIC PAIN AND PAIN ASSOCIATED WITH CLUSTER AND MIGRAIN HEAD PAIN
CARBAMATE COMPOUNDS FOR USE FOR PREVENTION OR TREATMENT OF NEUROPATHIC PAIN AND PAIN ASSOCIATED WITH CLUSTER AND MIGRAIN HEAD PAIN
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机译:氨基甲酸酯化合物,用于预防或治疗神经痛性疼痛和伴有团簇和偏头痛的疼痛
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摘要
This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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