APPLYING BENZENESULFONYL(THIO)UREAS FOR TREATMENT AND PROPHYLAXIS OF DISTURBANCES IN VEGETATIVE NERVOUS SYSTEM AND APPLYING BENZENESULFONYL(THIO)UREAS IN COMBINATION WITH BETA-RECEPTOR BLOCKING AGENTS

摘要

FIELD: organic chemistry, medicine, pharmacy.;SUBSTANCE: invention relates to applying substituted benzenesulfonylureas and -thioureas of the formula (I) for preparing a medicinal agent used for treatment and prophylaxis of disturbances in vegetative nervous system. In particular, invention relates to treatment and prophylaxis of disturbances associated with vagus nerve, for example, in cardiovascular diseases, and to applying compounds of the formula (I) in combination with beta-receptor blocking agents. Also, invention relates to products and pharmaceutical compositions that comprise at least one substance among compounds of the formula (I) and at least one beta-receptor blocking agent, and to new compounds also. Invention provides enhancing effectiveness in treatment.;EFFECT: valuable medicinal properties of compounds and pharmaceutical compositions.;22 cl, 2 tbl, 6 ex