APPLYING 2-IMIDAZOLYL-SUBSTITUTED CARBINOLS FOR PREPARING MEDICINAL AGENT FOR TREATMENT OR PROPHYLAXIS OF DISEASES CAUSED BY ISCHEMIC STATES

摘要

FIELD: organic chemistry, medicine, pharmacy.;SUBSTANCE: invention proposes applying the known 2-imidazolyl-substituted carbinols as inhibitor of Na⁺/H⁺ exchange in treatment or prophylaxis of diseases caused by ischemia (myocardium infarction, stenocardia, heart ischemic state, ischemic state of peripheral and central nervous system, insult, shock state, hypoxic states of donor organs in removing, storage and transplantation in the recipient body). Also, compounds can be used as anti-arrhythmic agents with cardioprotective effect and for prophylaxis of high blood pressure genesis in essential hypertension.;EFFECT: valuable medicinal properties of compounds.;10 cl, 2 ex