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Microcapsule immobilizing species for use in chemistry, food- or pharmaceutical technologies is stable when stored in concentrated medium and is ruptured on slight stressing following dilution

机译:用于化学,食品或制药技术的固定化微胶囊物质在浓缩培养基中储存时稳定,并且在稀释后受到轻微压力时会破裂

摘要

The capsule is stable in storage in a concentrated medium and on dilution is ruptured by slight mechanical stressing. Its core is completely enclosed by a matrix. The core is surrounded by multilayers. The casing includes a layer which is bonded electrostatically or covalently with the adjacent layer(s). Layer(s) are applied by solids coating and by membrane-forming fluid coating. At least one layer is formed by coating and complex formation. The core is a spherical droplet formed by precipitation, ionic effects or a temperature gradient. An oil or other material non-miscible with it, e.g. a hydrocarbon or hydrocarbon mixture, surrounds immobilized material in the core matrix. The substance to be immobilized forms a suspension with a second substance in the capsule interior, which forms a phase boundary with the matrix material. Other corresponding forms, e.g. a fluid/fluid emulsion or a solid phase are described. Cells or microorganisms may be contained in the core. Coating is carried out in a fluidized bed or flowing bed process. During drying in this process, additional solid is blown in. This forms a membrane on the capsule surface. All substances involved are food-compatible. Further variants and developments of the microcapsule are described in accordance with the foregoing principles.
机译:胶囊在浓缩培养基中稳定储存,稀释后由于轻微的机械应力而破裂。它的核心完全被矩阵包围。核心被多层包围。外壳包括与相邻层静电或共价键合的层。通过固体涂层和成膜流体涂层来施加层。通过涂覆和复合物形成形成至少一层。核是通过沉淀,离子效应或温度梯度形成的球形液滴。与之不混溶的油或其他物质,例如碳氢化合物或碳氢化合物混合物包围核心基质中的固定材料。待固定的物质与第二种物质在胶囊内部形成悬浮液,第二种物质与基质材料形成相界。其他对应形式,例如描述了流体/流体乳液或固相。细胞或微生物可以包含在核心中。涂覆在流化床或流化床工艺中进行。在此过程中的干燥过程中,会吹入额外的固体。这会在胶囊表面形成膜。涉及的所有物质均与食物相容。根据前述原理描述了微囊的其他变体和发展。

著录项

  • 公开/公告号DE102004005054A1

    专利类型

  • 公开/公告日2005-08-18

    原文格式PDF

  • 申请/专利权人 CAVIS MICROCAPS GMBH;

    申请/专利号DE20041005054

  • 发明设计人 POMMERSHEIM RAINER;

    申请日2004-01-31

  • 分类号B01J13/02;C08J7/04;A61K9/48;

  • 国家 DE

  • 入库时间 2022-08-21 22:00:56

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