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Use of Morinda citrifolia to inhibit phosphodiesterase enzymes, increase the body energy and reduce allergic and asthmatic reactions
Use of Morinda citrifolia to inhibit phosphodiesterase enzymes, increase the body energy and reduce allergic and asthmatic reactions
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机译:利用巴戟天抑制磷酸二酯酶,增加人体能量并减少过敏和哮喘反应
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摘要
Inhibiting a phosphodiesterase enzyme in a mammal comprising administration of a composition (I) comprising Morinda citrifoliafruit juice concentrate, is new. Independent claims are also included for methods for: (1) reducing allergy reactions, increase the body energy of a mammal and to reduce asthma reactions comprising administration of (I) to inhibit the action of a PDE enzyme thereby increasing the level of cyclic adenosine monophosphate (cAMP), decreasing immunoglobulin E and decreasing the secretion of histamine to decrease the allergic reaction; (2) increasing cAMP level and increasing the amount of glucose produced to increase the body energy of the mammal; and (3) increasing the level of cAMP and relaxing the muscle around the mammal's airways to decrease the severity of the reaction to asthma respectively. ACTIVITY : Antiallergic; Antiasthmatic. MECHANISM OF ACTION : Phosphodiesterases (PDEs) inhibitor. The ability of (I) to inhibit phosphodiesterases (PDE-6) was tested in Bovine retinal rod outer segments using biochemical assay. The median inhibitory concentration of (I) was 0.334%.
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