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immunoreaktive peptidische ctl epitope from human cytomegalovirus pp150
immunoreaktive peptidische ctl epitope from human cytomegalovirus pp150
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机译:人类巨细胞病毒pp150的免疫反应肽ctl表位
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摘要
The invention provides peptides which are immunogenic epitopes recognized by CD8+ class I MHC restricted cytotoxic T-lymphocytes of patients harboring latent cytomegalovirus (HCMV) infection. The peptides are capable of activating CTL in the absence of active viral replication, and thus are useful for eliciting a cellular immune response against HCMV by normal and immunodeficient subjects. Vaccines against HCMV, with and without adjuvants, and immunological and diagnostic reagents are disclosed.
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