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Production of microparticles, especially for sustained release of peptide drugs, comprises coacervation of a solution of an active ingredient and a solution of a biodegradable encapsulating polymer
Production of microparticles, especially for sustained release of peptide drugs, comprises coacervation of a solution of an active ingredient and a solution of a biodegradable encapsulating polymer
Production of microparticles by coacervation comprises adding a solution of an active ingredient (I) to a solution of a biodegradable encapsulating polymer (II) to form a mixture in which (I) precipitates, adding a nonsolvent for (I) and (II), adding a hardener, and filtering and drying the microparticles. An independent claim is also included for microparticles produced as above. ACTIVITY : None given. MECHANISM OF ACTION : None given.
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