New derivatives of 3-amino-4,5-dihydrothiophene and their use in cosmetic compositions to lighten and brighten the skin, prevent browning and remove brown patches such as age spots

摘要

New derivatives of 3-amino-4,5- dihydrothiophene in compositions as a whitening and/or lightening agent for the skin and/or the beard and/or the hair. New derivatives of formula (II) in compositions as a whitening and/or lightening agent for the skin and/or the beard and/or the hair. [Image] R11-6C alkyl; R2H, 1-6C alkyl or alkoxy, aryl (e.g. phenyl or naphthyl or anthracenyl) optionally substituted (e.g. with one or more halogen or 1-6C alkyl or 1-6C alkoxy or CF3 or hydroxy or amino itself optionally substituted with one or two 1-6C alkyl), optionally substituted heteroaryl (e.g. mono or bicyclic group containing at least one 5-11 link aromatic cycle and 1-5 N or O or S); R3-CO-R4, -CO-OR4, -CO-NH-R4, -CO-A-OR4, -CO-A-SR4, CO- A-CO-OR4; R41-6C alkyl, 3-8C cycloalkyl, aryl (e.g. phenyl or naphthyl or anthracenyl optionally substituted with one or more halogen or 1-6C alkyl or 1-6C alkoxy or CF3 or hydroxy or amino itself optionally substituted with one or two 1-6C alkyl), optionally substituted heteroaryl (e.g. mono or bicyclic group containing at least one 5-11 link aromatic cycle and 1-5 N or O or S); A : 2-6C alkylene. Independent claims are included for: (1) Use of known and new derivatives of Formula (I)/(II); (2) A composition comprising the new derivatives in a physically acceptable medium; (3) A cosmetic procedure for whitening and/or lightening human skin and/or beard and/or hair comprising application of a composition comprising derivatives of Formula (I)/(II); (4) A cosmetic procedure for hindering the browning of the skin comprising application of a composition comprising derivatives of Formula (I)/(II); (5) A cosmetic procedure for eliminated brown pigmented patches and/or age spots from human skin comprising application of a composition comprising derivatives of Formula (I)/(II). [Image] R'3H, -CO-R4, -CO-OR4, -CO-NH-R4, -CO-A-OR4, -CO-A-SR4, CO- A-CO-OR4.