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Production of soluble inclusion compounds, comprising contacting mixture of sparingly soluble active substance and host molecule with supercritical fluid, and treating product with interaction agent
Production of soluble inclusion compounds, comprising contacting mixture of sparingly soluble active substance and host molecule with supercritical fluid, and treating product with interaction agent
Soluble inclusion compounds are prepared by mixing a sparingly soluble active substance with a host molecule, contacting the mixture with a dense fluid under pressure in the presence of a diffusion agent, recovering the resulting complex and mixing the complex with an interaction agent. An independent claim is also included for a soluble inclusion compound produced as above. ACTIVITY : Analgesic; Antipyretic; Antibiotic; Antiinflammatory; Antiulcer; Hypotensive; Neuroleptic; Antidepressant. MECHANISM OF ACTION : None given.
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