THERAPEUTIC/PREVENTIVE AGENT FOR DIABETES AND/OR OBESITY, METHOD AND KIT FOR EVALUATING ANTIDIABETES AND/OR ANTIOBESITY ACTION, AND METHOD AND KIT FOR SCREENING ANTIDIABETES AND/OR ANTIOBESITY MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide a therapeutic/preventive agent for diabetes and/or obesity effective not only in treating diabetes and obesity but in preventing them.;SOLUTION: The therapeutic and/or preventive agent for diabetes and/or obesity contains gingerols as an effective ingredient, specifically inhibits/prevents reduction of the amount of adiponectin expression caused by a rise of the amount of expression of TNF-α and does not raise the amount of adiponectin expression in the normal state in which the amount of expression of TNF-α is low. The therapeutic and/or preventive agent for diabetes and/or obesity can be daily ingested and is effective for preventing diabetes and obesity. A method and a kit for evaluating antidiabetes and/or antiobesity action using the amount of expression of adiponectin in matured fat cells as a marker and a method and a kit for screening antidiabetes and/or antiobesity materials are provided.;COPYRIGHT: (C)2006,JPO&NCIPI