Methods and compositions for identifying therapeutic agents for atherosclerotic plaque lesions

摘要

The present invention relates to a method for monitoring the growth, erosion, rupture or stability of an atherosclerotic plaque comprising the analysis of the differential expression of at least one gene coding a protein chosen among Stearoyl CoA deasturase, Aldose reductase and aldehyde reductase, Sphingomyelinase, Acid ceramidase, Ceramide glucosyl transferase, Sphingosin phosphate liase, Thymosine beta 4, Aldehyde dehydrogenase, ATPase Ca++ binding protein and CD163.