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Method for increasing use pharmaceutical preparations, in their formulations, the bioavailability of the drug substance and orally administered

机译:药物制剂及其制剂中药物的生物利用度的增加使用方法和口服方法

摘要

One emulsifier, solvent, and relates to a pharmaceutical formulation comprising one lipid, the present invention, the emulsifier here and / or at least assist one emulsifier at least: 1 weight ratio of solvent (Smix) and auxiliary / or emulsifiers: 1 to 9: 1, and 0% total lipid ratio is (v / v), and thereby, to be at least partially inhibit the intestinal outflow system and / or at least one enteric at least one enzyme I characterized. Drug substance which is a substrate for intestinal outflow system and gut metabolism / or enzymes and / or lipophilic, these formulations can be used to increase the bioavailability of the particular steroid.
机译:一种乳化剂,溶剂,并且涉及包含一种脂质的药物制剂,本发明,此处的乳化剂和/或至少辅助一种乳化剂的比例为:溶剂(Smix)与辅助/或乳化剂的重量比至少为:1至9总脂质比为:1:1,并且> 0%是(v / v),因此,至少部分抑制了肠道流出系统和/或至少一种肠溶至少一种酶的特征。药物是肠道流出系统和肠道代谢/或酶和/或亲脂性的底物,这些制剂可用于增加特定类固醇的生物利用度。

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