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Taxoid conjugates - camptothecin anti-mitotic agents and as an anti-tumor drug

机译:紫杉类共轭物-喜树碱抗有丝分裂剂和抗肿瘤药

摘要

Compounds according to formula I: C'-L-T (I), wherein C' is a camptothecin group; L is a linking moiety; T is a taxoid group, pharmaceutically acceptable salt thereof. The compounds are useful in, among other things, treating cancer in subjects in need thereof, including cellular differentiation, and inhibiting cellular mitosis.
机译:根据式I的化合物:C'-L-T(I),其中C'是喜树碱基团; L是连接部分; T是紫杉类基团,其药学上可接受的盐。所述化合物尤其可用于治疗有此需要的受试者的癌症,包括细胞分化和抑制细胞有丝分裂。

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