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Semiconductor base structure for molecular electronics and molecular electronic-based biosensor devices and a method for producing such a semiconductor base structure

机译:用于分子电子学和基于分子电子的生物传感器装置的半导体基础结构及其制造方法

摘要

The invention concerns a structured semiconductor surface as basis for molecular electronics or molecular electronics-based bio-sensors. The starting point is a heterostructure consisting of two undoped layers of a semiconductor material that are separated by an extremely thin (a few nm) layer of a different semiconductor material. This material stack is cleaved perpendicular to the layer planes and the middle layer is selectively etched. Source- and drain contacts for conductive organic “wires” are by built by evaporation with a thin metal film. The middle conductive layer can be employed as electrostatic gate. An assembly for contacting a few up to single wires can be obtained by two sequential separations and evaporations. Possible organic wires are e.g. molecules with conjugated (E-electron system, DNA-oligonucleotides or carbon nanotubes. By means of a further functionalisation with receptors for biomolecular recognition (antibodies, proteins) an employment as highly sensitive biosensor for detection, analysis and quantification of special biomolecules and their mutual interaction becomes possible (e.g. DNA-protein interaction).
机译:本发明涉及结构化的半导体表面作为分子电子学或基于分子电子学的生物传感器的基础。起点是异质结构,该异质结构由半导体材料的两个非掺杂层组成,该两个非掺杂层被另一种半导体材料的极薄(几纳米)层隔开。垂直于层平面劈开该材料叠层,并且选择性地蚀刻中间层。导电有机“线”的源极和漏极触点通过蒸发形成一层薄金属膜。中间导电层可以用作静电栅​​极。通过两次连续的分离和蒸发,可以获得用于接触几根至多根单线的组件。可能的有机导线例如具有共轭分子(电子系统,DNA寡核苷酸或碳纳米管)的分子,通过与受体进行进一步的功能化以识别生物分子(抗体,蛋白质),成为一种高度灵敏的生物传感器,用于检测,分析和定量特殊生物分子及其相互之间相互作用成为可能(例如DNA-蛋白质相互作用)。

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