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Antagonizing nk-1 receptors inhibits consumption of substances of abuse
Antagonizing nk-1 receptors inhibits consumption of substances of abuse
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机译:拮抗nk-1受体可抑制滥用物质的消耗
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摘要
This invention pertains to the surprising discovery that administration of one or more NK1 receptor antagonists to a mammal can inhibit self-administration of a substance of abuse (e.g. alcohol). In one embodiment, this invention provides a method of inhibiting or reducing self-administration of a substance of abuse by a mammal. The method involves administering to the mammal an NK1 receptor antagonist in a concentration sufficient to reduce self-administration of a substance of abuse and/or craving for a substance of abuse (e.g. ethanol).
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