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Antibody composition and passive immunization against pregnancy-induced hypertension

机译:抗妊娠高血压的抗体组成和被动免疫

摘要

A composition is provided to prevent, limit the effects of, delay the onset of, or treat one or more of the causes, symptoms or complications of gestational hypertension, preeclampsia, eclampsia and/or intrauterine growth restriction. The composition comprises a therapeutically effective amount of an antibody that reacts immunologically with or binds digoxin and has a high dose of digoxin binding capacity as the active ingredient. There is also provided a method of preventing, limiting the effects of, delaying the onset of, or treating a cause, symptom or complication of gestational hypertension, preeclampsia, eclampsia or intrauterine growth restriction, comprising the step of administering to a mammal a composition comprising a therapeutically effective amount of an antibody that reacts immunologically with or binds digoxin and has a high dose of digoxin binding capacity.
机译:提供一种组合物以预防,限制其作用,延迟其发作或治疗妊娠高血压,先兆子痫,子痫和/或子宫内生长受限的原因,症状或并发症中的一种或多种。该组合物包含治疗有效量的抗体,该抗体与地高辛发生免疫反应或结合,并具有高剂量的地高辛结合能力作为活性成分。还提供了预防,限制妊娠高血压,先兆子痫,子痫或子宫内生长受限的原因,症状或并发症的发作,症状的发作或治疗的方法,该方法包括向哺乳动物施用包含以下成分的组合物的步骤:与地高辛发生免疫反应或结合并具有高剂量的地高辛结合能力的治疗有效量的抗体。

著录项

  • 公开/公告号US2006134106A1

    专利类型

  • 公开/公告日2006-06-22

    原文格式PDF

  • 申请/专利权人 CHARLES DAVID ADAIR;

    申请/专利号US20050317378

  • 发明设计人 CHARLES DAVID ADAIR;

    申请日2005-12-23

  • 分类号A61K39/395;

  • 国家 US

  • 入库时间 2022-08-21 21:47:43

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