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p49/STRAP is a novel protein involved in gene regulation and cell proliferation
p49/STRAP is a novel protein involved in gene regulation and cell proliferation
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机译:p49 / STRAP是一种参与基因调控和细胞增殖的新型蛋白质
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摘要
The invention provides isolated p49/STRAP protein, and isolated nucleic acids encoding a p49/STRAP protein. The inventors have discovered a new protein, named p49/STRAP that is expressed in cardiac tissue and other tissues in mammals. The p49/STRAP protein binds to serum response factor (SRF) and regulates transcription of SRF-responsive genes in the heart. p49/STRAP is also discovered to inhibit tumor cell proliferation, and thus the invention provides a method of inhibiting cancer cell proliferation by contacting the cells with p49/STRAP.
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