首页>
外国专利>
Methods of MHC class II epitope mapping, detection of autoimmune T cells and antigens, and autoimmune treatment
Methods of MHC class II epitope mapping, detection of autoimmune T cells and antigens, and autoimmune treatment
展开▼
机译:MHC II类表位作图,自身免疫T细胞和抗原的检测以及自身免疫治疗的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides of using multimeric MHC class II/peptide complexes. In one aspect, methods provided for identifying MHC class II-restricted immune epitopes of a predetermined polypeptide antigen. Methods for identifying an immunostimulatory epitope for a predetermined polypeptide antigen are provided. In a related aspect, methods for screening a therapeutic polypeptide agent for an MHC class II epitope are provided. In other aspects, methods for modulating T cells and for determining or monitoring an MHC class II-restricted immune status of a patient are also provided.
展开▼