Self-assembled arrays of lipid-bilayer vesicles

摘要

High-density arrays of attoliter volume elements can be created within minutes in a parallel and effortless manner by using self-assembly of nanometer-sized components (e.g., lipid vesicles containing (bio)chemicals) based on biological recognition. The ultrasmall volumes allow localization to a predefined position of a few or single molecules, and then screening for their (bio)chemical properties or performing confined (bio)chemical reactions.