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Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent
Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent
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机译:具有效应器和亲和功能的抗淋巴瘤靶向剂通过三功能试剂连接
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摘要
A medical agent comprising a reagent conjugated to an anti-lymphoma antibody is disclosed, as well as a kit containing said medical agent, use of said medical agent, and a method for treatment of lymphoma. The reagent may comprise an effector, e.g. an antitumor agent or a diagnostic marker, and an affinity ligand enabling extracorporeal clearance of the agent. The three components are bound by a trifunctional linker. 展开▼
机译:公开了包含与抗淋巴瘤抗体缀合的试剂的药物,以及包含所述药物的试剂盒,所述药物的用途和治疗淋巴瘤的方法。所述试剂可包含效应子,例如。抗肿瘤剂或诊断标记物,以及能够清除该试剂的亲和配体。这三个组件由三功能连接子约束。 <图像alt =“嵌入式图像” file =“ US20060222588A1-20061005-C00001.GIF” he =“ 133.10mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi =“ 75.27mm” /> Chemistry>
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