embedded image"/> Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent
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Antilymphoma targeting agents with effector and affinity functions linked by a trifunctional reagent

机译:具有效应器和亲和功能的抗淋巴瘤靶向剂通过三功能试剂连接

摘要

A medical agent comprising a reagent conjugated to an anti-lymphoma antibody is disclosed, as well as a kit containing said medical agent, use of said medical agent, and a method for treatment of lymphoma. The reagent may comprise an effector, e.g. an antitumor agent or a diagnostic marker, and an affinity ligand enabling extracorporeal clearance of the agent. The three components are bound by a trifunctional linker. embedded image
机译:公开了包含与抗淋巴瘤抗体缀合的试剂的药物,以及包含所述药物的试剂盒,所述药物的用途和治疗淋巴瘤的方法。所述试剂可包含效应子,例如。抗肿瘤剂或诊断标记物,以及能够清除该试剂的亲和配体。这三个组件由三功能连接子约束。 <图像alt =“嵌入式图像” file =“ US20060222588A1-20061005-C00001.GIF” he =“ 133.10mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi =“ 75.27mm” />

著录项

  • 公开/公告号US2006222588A1

    专利类型

  • 公开/公告日2006-10-05

    原文格式PDF

  • 申请/专利权人 BENGT SANDBERG;RUNE NILSSON;

    申请/专利号US20030538669

  • 发明设计人 BENGT SANDBERG;RUNE NILSSON;

    申请日2003-12-12

  • 分类号A61K51/00;A61K39/395;C07K16/46;C07K16/30;

  • 国家 US

  • 入库时间 2022-08-21 21:45:11

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