Method of inhibiting neural transmission mediated by serotonin-2a and enhancing sensorimotor gating

摘要

Disclosed are methods for treating neuropsychiatric disorders and disorders associated with sensorimotor gating deficits and/or prepulse inhibition disorders and improving sensorimotor gating in normal subjects. Also provided are animal models useful for identifying agents that modulate sensorimotor gating activity for preclinical testing of psychotropic drugs.