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Diagnosis of disease and monitoring of therapy using gene expression analysis of peripheral blood cells
Diagnosis of disease and monitoring of therapy using gene expression analysis of peripheral blood cells
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机译:利用外周血细胞基因表达分析诊断疾病并监测治疗
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摘要
Disclosed are methods to diagnose a patient that has a pulmonary disease, and particularly, pulmonary arterial hypertension, using biomarkers that are differentially regulated in the peripheral blood cells of patients with such disease as compared to individuals that do not have the disease. Also disclosed are methods to diagnose a patient that has idiopathic pulmonary arterial hypertension as compared to pulmonary arterial hypertension associated with secondary causes. Pluralities of nucleotides and antibodies useful in the invention are described. Methods of identifying compounds with the potential to treat pulmonary arterial hypertension (PAH) are also described.
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