Methods and compositions for controlling hair follicle stem cell fate

摘要

The present invention relates to mutant hair follicle stem cells possessing an inactive Bmpr1a receptor, wherein such mutant hair follicle stem cells proliferate and undergo self-renewal. Additionally, the present invention relates to compositions and methods for induction of hair follicle stem cell proliferation in vivo and in vitro. The present invention also relates to mutant Bmpr1a organisms and tumor cells.