Biliverdin reductase fragments and variants, and methods of using biliverdin reductase and such fragments and variants

摘要

One aspect of the present invention relates to a method of regulating protein kinase C activity that includes contacting human protein kinase C selected from the group of isozymes α, β, and γ with a mammalian biliverdin reductase or a fragment thereof with protein kinase C regulatory activity.