Cis-3,5-disubstituted-dihydro-furan-2-ones and the preparation and use thereof

摘要

The present invention relates to an improved process to prepare cis-3-dihydrocarbylmethano-5-hydrocarbyidihydro-furan-2-ones. The present invention also relates to novel compositions of matter comprising enantiomerically pure cis-3-dihydrocarbylmethano-5-hydrocarbyldihydro-furan-2-ones, being the (3S,5S), (3R,5R), (3S,5R), or (3R,5S) optically pure isomers, and a new, more cost efficient process to prepare said optically pure isomers.