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Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
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机译:在没有复制感受态腺病毒的情况下可用于生产E1缺失的腺病毒的细胞系和构建体
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摘要
Novel cell lines useful for trans-complementing E1-deleted adenoviral vectors are described. The cell lines are capable of providing high yields of E1-deleted adenoviral vectors in the absence of replication-competent adenovirus over multiple passages.
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