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Antibodies of the P2Y10 receptor useful in altering T lymphocyte function
Antibodies of the P2Y10 receptor useful in altering T lymphocyte function
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机译:P2Y10受体的抗体可用于改变T淋巴细胞的功能
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摘要
The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.
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