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Methods and compositions for stabilizing microtubules and intermediate filaments in striated muscle cells
Methods and compositions for stabilizing microtubules and intermediate filaments in striated muscle cells
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机译:稳定横纹肌细胞中微管和中间细丝的方法和组合物
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摘要
The present invention discloses new muscle ring finger (MURF) proteins designate MURF-1, MURF-2 and MURF-3. The genes encoding these MURFs also are provided. MURFs interact with microtubules and thus play a role in cytoskeletal function, mitosis and cell growth. Thus, the uses of MURFs in diagnosis, treatment and drug screening, in particular relation to cardiomyopathies, are described.
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