首页> 外国专利> Process for producing an iron-dextran compound, iron-dextran compound produced according to said process, pharmaceutical composition for prophylaxis or treatment of iron-deficiency and use of said compound for the preparation of parenterally administrable pharmaceutical composition

Process for producing an iron-dextran compound, iron-dextran compound produced according to said process, pharmaceutical composition for prophylaxis or treatment of iron-deficiency and use of said compound for the preparation of parenterally administrable pharmaceutical composition

机译:铁-葡聚糖化合物的生产方法,根据所述方法生产的铁-葡聚糖化合物,预防或治疗铁缺乏的药物组合物以及所述化合物在制备肠胃外给药药物组合物中的用途

摘要

In a process for producing an iron-dextran compound for use in parenteral treatment of iron-deficiency in humans or animals a stable compound of desired relatively low molecular weight is obtained by using first hydrogenation and then oxidation to convert reducing terminal groups on the dextran molecules before reaction with the iron. By varying the ratio of hydrogenated groups to oxygenated groups the average molecular weight of the resulting iron-dextran compound can be varied.
机译:在用于肠胃外治疗人或动物缺铁的铁-右旋糖酐化合物的制备方法中,通过首先氢化然后氧化以转化右旋糖酐分子上的还原端基,得到所需分子量相对较低的稳定化合物。与铁反应之前。通过改变氢化基团与氧化基团的比例,可以改变所得铁-葡聚糖化合物的平均分子量。

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