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Congener independent detection of microcystin and nodularin congeners

机译:微囊藻毒素和结节蛋白同类物的同类物独立检测

摘要

The present invention relates to a protienaceous compound or functionally active derivative or part thereof having a binding site for a group represented by formula (I) which is part of a group of toxins derived from various cyanobacteria, to a method for its production, to diagnostic kits and to an affinty matrix (e.g. for use in immunoaffinity columns, online detection and purifications devices) containing the proteinaceous compound as well as to methods for substantially decreasing the amount of a compound containing the group represented by formula (I) in fluids or for concentrating compounds, e.g. toxins, containing the group represented by formula (I) from fluids such as crude water samples, extracts of algae or other tissue samples, e.g. to determine toxin concentrations.
机译:本发明涉及一种蛋白质类化合物或功能活性衍生物或其部分,其具有与式(I)表示的基团的结合位点,所述式(I)表示的基团是衍生自各种蓝细菌的一组毒素的一部分,试剂盒和含有蛋白质化合物的亲和基质(例如,用于免疫亲和柱,在线检测和纯化装置)以及实质上减少液体中含有式(I)代表基团的化合物的量的方法或浓缩化合物,例如毒素,其包含诸如水样品,藻类提取物或其他组织样品(例如水)的液体中的式(I)表示的基团。确定毒素浓度。

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