Soluble Granules of bromhexine hydrochloride and bromhexine, Process for its production and its use

摘要

Rapidly soluble Granules, obtainable by (a) an aqueous liquid for production of granular, contains at least a Binding Agent, and (b) spray application to granular Liquid obtained in STEP (a) in a fluidized Layer, by a procedure in countercurrent to a T Constant emperature of incoming Air, on a vehicleWhich contains at least a carbohydrate used bromhexine hydrochloride and bromhexine acu00eddo / Citric, independently of each other in Liquid, granular and / or on the vehicle.For the first time makes available through the teaching according to the invention, a water soluble Granules containing bromhexine hydrochloride bromhexine as active substance / Granules according to this Invention, in spite of bromhexine hydrochloride and bromhexine, itself Sparingly Soluble in water, soluble in water,That is to say that the grabulado dissolves completely in Water Environment in the course of a few minutes and release the active substance in its full extension.