Use of eif-5a siRNA and antisense polynucleotides to inhibit specific apoptosis / delete an inflammatory response.

摘要

Method to remove or reduce the apoptosis in a cell with an agent that Inhibits or reduces the expression of eif-5a apoptosis or the DHS (deoxihiposina synthase). An antisense oligonucleotide of Apoptosis specific eif-5a where endogenous antisense oligonucleotide suppressed the expression of Apoptosis specific eif-5a in a cell.The antisense oligonucleotide on the apoptosis specific eif-5a is encoded with a Nucleotide sequence of SEQ ID no. 20, 35, 41, 37 or 39. AN EXPRESSION Vector for transfection of Mammalian Cell comprising the antisense oligonucleotide and Regulatory Sequences in the United Operational form antisense oligonucleotide in this cell.Method of inhibiting the expression of Apoptosis specific eif-5a in a cell. The Method manages siRNA in vivo Lung cells of a Mammal.