Method of treating, preventing or inhibiting a snc disorder and / or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a selective cyclooxygenase-2 inhibitor and their formulations.

摘要

"METHOD OF TREATMENT, PREVENTION OR INHIBITION OF A CNS DISORDER AND / OR PAIN AND INFLAMMATION USING A DULOXETIN, VENLAFAXIN OR ATOMOXETIN ASSOCIATION AND A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2A AND ITS FORCES A method of treating, preventing or inhibiting a CNS disorder and / or pain and inflammation or an inflammation-associated disorder in an individual in need of such treatment or prevention provides for treating the individual with duloxetine, venlafaxine or atomoxetine and a selective cyclooxygenase-2 inhibitor. or the prodrug thereof, wherein the amount of duloxetine, venlafaxine or atomoxetine and the amount of a selective cyclooxygenase-2 inhibitor or prodrug thereof together constitute an effective amount of treatment, prevention or inhibition of the formulation to suppress the disorder. CNS, pain and inflammation, or the disorder associated with inflammation. Also disclosed are pharmaceutical compositions and formulations containing duloxetine, venlafaxine or atomoxetine and a selective cyclooxygenase-2 inhibitor.